A sensitivity analysis examining how varying ligament properties in OpenSim impacts on estimating ACL tension, with potential applications in a six-degree-of-freedom knee model

This thesis presents a sensitivity analysis evaluating the influence of Anterior Cruciate Ligament (ACL) properties on the tissue's biomechanical response during various motor tasks. The methodology comprised two main phases. First, a comparative analysis of three OpenSim musculoskeletal models was conducted to evaluate differences in kinematic and kinetic variables. Subsequently, a model aimed at optimizing the ACL slack length was implemented and benchmarked against the others models. In conclusion, this study highlights the critical importance of accurately defining ACL parameters in musculoskeletal modeling to ensure simulation accuracy and reliability in force estimation.