The present thesis aims to define and apply an advanced methodological protocol for the three-dimensional (3D) evaluation of the upper airways in patients undergoing orthognathic surgery. Overcoming the limitations of traditional two-dimensional (2D) cephalometry, the study is based on a retrospective clinical database of computed tomography (CT) scans acquired during both pre-operative and post-operative phases. The methodology involves accurate volumetric segmentation of the pharyngeal airway column. Using dedicated software, the upper airways will be divided into their main anatomical compartments (nasopharynx, oropharynx, and hypopharynx) through the identification of specific anatomical landmarks and standardized reference planes (such as planes passing through the nasal spine or cervical vertebrae). The final aim is to correlate the magnitude and direction of maxillo-mandibular surgical movements with the actual morpho-functional remodeling of the airway space, providing clinically relevant data to improve surgical predictability and to better assess the impact of surgery on the patient’s respiratory function.
Il presente lavoro di tesi si pone l'obiettivo di definire e applicare un protocollo metodologico avanzato per la valutazione tridimensionale (3D) delle vie aeree superiori in pazienti sottoposti a chirurgia ortognatica. Superando i limiti della tradizionale cefalometria 2D bidimensionale, lo studio sfrutta un database clinico retrospettivo di tomografie (CT) acquisite nelle fasi pre- e post-operatorie. La metodologia prevede l'esecuzione di una segmentazione volumetrica accurata della colonna d'aria faringea. Utilizzando software dedicati, le vie aeree verranno suddivise nei loro compartimenti anatomici principali (nasofaringe, orofaringe e ipofaringe) attraverso l'identificazione di specifici punti di repere e piani di riferimento standardizzati (come i piani passanti per la spina nasale o le vertebre cervicali). Lo scopo finale è correlare l'entità e la direzione dei movimenti chirurgici maxillo-mandibolari con l'effettivo rimodellamento morfo-funzionale dello spazio aereo, fornendo dati clinici utili per migliorare la predicibilità dell'intervento e l'impatto sulla capacità respiratoria del paziente.
Sviluppo di un protocollo computazionale per l’analisi morfometrica delle vie aeree superiori: studio retrospettivo su pazienti ortognatici
FAGIANI, SARA
2025/2026
Abstract
The present thesis aims to define and apply an advanced methodological protocol for the three-dimensional (3D) evaluation of the upper airways in patients undergoing orthognathic surgery. Overcoming the limitations of traditional two-dimensional (2D) cephalometry, the study is based on a retrospective clinical database of computed tomography (CT) scans acquired during both pre-operative and post-operative phases. The methodology involves accurate volumetric segmentation of the pharyngeal airway column. Using dedicated software, the upper airways will be divided into their main anatomical compartments (nasopharynx, oropharynx, and hypopharynx) through the identification of specific anatomical landmarks and standardized reference planes (such as planes passing through the nasal spine or cervical vertebrae). The final aim is to correlate the magnitude and direction of maxillo-mandibular surgical movements with the actual morpho-functional remodeling of the airway space, providing clinically relevant data to improve surgical predictability and to better assess the impact of surgery on the patient’s respiratory function.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/109291