The field of dental medicine frequently makes use of devices for the treatment of complex alveolar bone defects. These devices are designed as customized grids, mainly manufactured in titanium in order to achieve a suitable combination of mechanical and biological properties for their application. However, the use of titanium scaffolds presents the drawback of requiring surgical removal or being subject to rejection phenomena. This has led to the need to replace this material with one that is more stable, drillable, or resorbable, investigating new alternatives through experimental tests on animal models. Therefore, the aims of the present thesis study are to evaluate bone growth through microCT analysis and to develop geometric modeling approaches for the scaffolds.
Il campo della medicina odontoiatrica fa spesso uso di dispositivi per il trattamento di difetti ossei alveolari complessi. I suddetti dispositivi si presentano come delle griglie personalizzate prodotte principalmente in titanio per ottenere una combinazione di proprietà meccaniche e biologiche idonee al loro utilizzo. La fabbricazione in titanio dello scaffold presenta però il difetto di dover essere rimossa chirurgicamente o andare incontro a rigetto. Da ciò nasce la necessità di sostituire tale materiale con uno più stabile, forabile o riassorbibile, studiandone dei nuovi tramite test su cavie. Gli obiettivi del presente studio di tesi sono pertanto quelli di valutare l'accrescimento osseo (attraverso l'analisi delle microCT) e di sviluppo di approcci di modellazione geometrica degli scaffold.
Modellazione geometrica e analisi microtomografica di una griglia personalizzata bioriassorbibile per la rigenerazione ossea nel settore odontoiatrico
CARMINATI, LORENZO
2025/2026
Abstract
The field of dental medicine frequently makes use of devices for the treatment of complex alveolar bone defects. These devices are designed as customized grids, mainly manufactured in titanium in order to achieve a suitable combination of mechanical and biological properties for their application. However, the use of titanium scaffolds presents the drawback of requiring surgical removal or being subject to rejection phenomena. This has led to the need to replace this material with one that is more stable, drillable, or resorbable, investigating new alternatives through experimental tests on animal models. Therefore, the aims of the present thesis study are to evaluate bone growth through microCT analysis and to develop geometric modeling approaches for the scaffolds.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/111349