"Resting spontaneous blink rate and cognitive performance in Parkinson’s disease: an exploratory EOG study".

Parkinson's disease is a very common neurodegenerative disorder, primarily characterized by a range of motor symptoms known as parkinsonisms. The disease can also present a variety of non-motor features that significantly impact the patient’s quality of life, like the cognitive symptoms, which often evolve into Mild Cognitive Impairment or dementia. As such, identifying patients at risk of cognitive decline at an early stage is essential for improving prognosis and guiding clinical management, rendering biomarkers extremely important. Spontaneous blink rate is a non-invasive and cost-effective tool that has potential as an accessible future biomarker of PD. Given the need for future research, our study focused on the use of electrooculogram-assessed spontaneous blink rate and its relationship with various degrees of cognition in PD patients, with the hope of providing further insight into the disease and its mechanisms.