The conditions of concentration and relative humidity that favor the onset of segregative phenomena during the die filling step in the tablet production process are investigated. The research focuses on density-driven segregation of a binary mixture of caffeine, the API, and DCPA, the excipient. Results are compared with DEM simulations.
Density-induced segregation in particles flows
Poloni, Lorenzo
2019/2020
Abstract
The conditions of concentration and relative humidity that favor the onset of segregative phenomena during the die filling step in the tablet production process are investigated. The research focuses on density-driven segregation of a binary mixture of caffeine, the API, and DCPA, the excipient. Results are compared with DEM simulations.File in questo prodotto:
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Utilizza questo identificativo per citare o creare un link a questo documento:
https://hdl.handle.net/20.500.12608/24586