Two compartmental models of Phe and Tyr metabolism in healthy subjects were developed, by using two stable isotope tracer pulses administered intravenously. The simplest model provides a physiologically relevant overview of Phe and Tyr metabolism in terms of intervals of validity. The more complex one is uniquely identifiable, but makes a higher number of structural assumptions. These models could serve as a future reference in amino acids modeling

Compartmental Models for the Assessment of Net Whole Body Protein Breakdown Using a Pulse of Phenylalanine and Tyrosine Stable Isotopes in Humans

Mason, Alvise
2016/2017

Abstract

Two compartmental models of Phe and Tyr metabolism in healthy subjects were developed, by using two stable isotope tracer pulses administered intravenously. The simplest model provides a physiologically relevant overview of Phe and Tyr metabolism in terms of intervals of validity. The more complex one is uniquely identifiable, but makes a higher number of structural assumptions. These models could serve as a future reference in amino acids modeling
2016-04-21
Phenylalanine, Tyrosine, Stable Isotopes, Tracer Kinetics, Compartmental Model
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12608/25568