Investigating Parameters Ruling Cage to Cage Transformations

In the field of smart host-guest systems, supramolecular cages are an appealing class of compounds that, upon the trigger given by an external stimulus, can either experience disassembly, leading to the release of the guest, or change in size of their cavity, altering their binding selectivity. However, the aspects ruling these processes are still unclear. In this thesis, transformations of an imine cage induced by diamine exchange are kinetically investigated using both NMR and ESI-MS techniques, allowing to reveal how the guest size plays a crucial role in the rate of the process.