Multiple sclerosis (MS) is an inflammatory, neurodegenerative and demyelinating disease that involves the central nervous system (i.e. the brain, spinal cord and optic nerves). The resulting clinical picture is extremely complex due to its heterogeneity. In fact, there are multiple symptoms, both physical and cognitive, that can occur in conjunction with the diagnosis of MS. From a neuropsychological point of view, therefore, one of the challenges of recent times is represented by proposing innovative rehabilitation interventions (such as computerized ones), in order to enhance the cognitive abilities most involved in this pathology. Specifically, the present study aims to investigate the cognitive alterations present in the domains of memory and attention and at the same time is aimed at proposing a new rehabilitation strategy, based on the computerized training program Ms-Rehab. The study involved 30 patients with RRMS who performed computerized training on memory and attention for two months; All patients were evaluated, with the BRB-NT protocol, before and after the training and 3 months after the end of the training. The results, which showed an improvement in general cognitive performance after the training, represent a possible starting point for future studies.
La sclerosi multipla (SM) è una malattia infiammatoria, neurodegenerativa e demielinizzante che coinvolge il sistema nervoso centrale (ovvero encefalo, midollo spinale e nervi ottici). Il quadro clinico che ne deriva è estremamente complesso proprio per la sua eterogeneità. Molteplici, infatti, sono i sintomi, sia fisici che cognitivi, che possono presentarsi in concomitanza con la diagnosi di SM. Da un punto di vista neuropsicologico, quindi, una delle sfide degli ultimi tempi è rappresentata dal proporre degli interventi riabilitativi innovativi (come quelli computerizzati), al fine di potenziare le abilità cognitive maggiormente coinvolte in questa patologia. Nello specifico, il presente studio mira ad indagare le alterazioni cognitive presenti nei domini della memoria e dell’attenzione e allo stesso tempo è finalizzato a proporre una nuova strategia riabilitativa, fondata sul programma di training computerizzato Ms-Rehab. Lo studio ha coinvolto 30 pazienti con SM-RR che hanno svolto un training computerizzato su memoria e attenzione per due mesi; tutti i pazienti sono stati valutati, con il protocollo BRB-NT, prima e dopo il training svolto e a 3 mesi dalla fine del training. I risultati, che hanno mostrato un miglioramento nella prestazione cognitiva generale dopo il training, rappresentano un possibile punto di partenza per studi futuri.
Ms-rehab: una nuova frontiera di riabilitazione computerizzata per il potenziamento delle funzioni mnestico-attentive in un gruppo di pazienti con sclerosi multipla
LUCIBELLI, NIVES
2023/2024
Abstract
Multiple sclerosis (MS) is an inflammatory, neurodegenerative and demyelinating disease that involves the central nervous system (i.e. the brain, spinal cord and optic nerves). The resulting clinical picture is extremely complex due to its heterogeneity. In fact, there are multiple symptoms, both physical and cognitive, that can occur in conjunction with the diagnosis of MS. From a neuropsychological point of view, therefore, one of the challenges of recent times is represented by proposing innovative rehabilitation interventions (such as computerized ones), in order to enhance the cognitive abilities most involved in this pathology. Specifically, the present study aims to investigate the cognitive alterations present in the domains of memory and attention and at the same time is aimed at proposing a new rehabilitation strategy, based on the computerized training program Ms-Rehab. The study involved 30 patients with RRMS who performed computerized training on memory and attention for two months; All patients were evaluated, with the BRB-NT protocol, before and after the training and 3 months after the end of the training. The results, which showed an improvement in general cognitive performance after the training, represent a possible starting point for future studies.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/78581