Bipolar Disorder involves persistent deficits in social cognition that remain even during euthymic phases, negatively affecting patients’ interpersonal functioning. The study investigates the recognition of “moral” facial expressions (anger and disgust) in euthymic patients with type I and type II Bipolar Disorder. Using Network Analysis to integrate behavioral performance and gray matter volume measures, the research revealed that BD-I patients show a selective deficit in decoding these emotions compared with BD-II patients and healthy controls. At the neural level, BD-I is characterized by a reconfiguration of the fronto-limbic network. These findings suggest that the recognition of moral emotions may serve as a clinical marker for the development of personalized socio-cognitive rehabilitation interventions.
Il disturbo bipolare comporta deficit persistenti nella cognizione sociale che permangono anche durante le fasi di eutimia, influenzando negativamente il funzionamento interpersonale dei pazienti. Lo studio indaga il riconoscimento delle espressioni facciali "morali" (rabbia e disgusto) in pazienti con Disturbo Bipolare di tipo I e II in fase eutimica. Utilizzando la Network Analysis per integrare le performance comportamentali e i volumi della materia grigia, la ricerca ha rivelato che i pazienti BD-I presentano un deficit selettivo nella decodifica di queste emozioni rispetto ai BD-II e ai controlli sani. A livello neurale, il BD-I mostra una riconfigurazione del network fronto-limbico. Questi risultati suggeriscono che il riconoscimento delle emozioni morali possa fungere da marker clinico per sviluppare interventi di riabilitazione socio-cognitiva personalizzati.
Il giudizio morale nelle espressioni facciali: una network analysis nel disturbo bipolare eutimico
CORRADIN, ADELE MARIA
2025/2026
Abstract
Bipolar Disorder involves persistent deficits in social cognition that remain even during euthymic phases, negatively affecting patients’ interpersonal functioning. The study investigates the recognition of “moral” facial expressions (anger and disgust) in euthymic patients with type I and type II Bipolar Disorder. Using Network Analysis to integrate behavioral performance and gray matter volume measures, the research revealed that BD-I patients show a selective deficit in decoding these emotions compared with BD-II patients and healthy controls. At the neural level, BD-I is characterized by a reconfiguration of the fronto-limbic network. These findings suggest that the recognition of moral emotions may serve as a clinical marker for the development of personalized socio-cognitive rehabilitation interventions.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/109912