The sinuses of Valsalva are essential for the physiological function of the aortic valve and for preserving the aortic root. By generating vortical flow patterns, they facilitate the closure of the aortic valve and promote optimal coronary blood flow. After a brief description of the relevant anatomical region, the thesis presents the first studies on the subject conducted by the Bellhouse brothers. Before their work, only Leonardo da Vinci had recognized the importance of the sinuses of Valsalva, reaching conclusions that are consistent with current scientific evidence. Based on subsequent studies, several hemodynamic phenomena are then analyzed, including vortex formation, pressure drop, stresses acting on the valve leaflets, and coronary perfusion. These phenomena are examined under different conditions and, in many cases, by comparing an aortic root with the sinuses of Valsalva to one without them. A thorough understanding of the fluid dynamics of the sinuses of Valsalva is essential for the correct interpretation of pathological alterations of the aortic root and for the optimization of preventive and surgical strategies.
I seni di Valsalva sono essenziali per il fisiologico funzionamento della valvola aortica e la salvaguardia del distretto della radice aortica. Essi infatti, generando correnti vorticose, facilitano la chiusura della valvola aortica e favoriscono un ottimale flusso sanguigno coronarico. Dopo una breve descrizione dell’area anatomica d’interesse, vengono illustrati i primi studi sull’argomento svolti dai fratelli Bellhouse. Prima di loro, solo Leonardo da Vinci aveva colto l’importanza dei seni di Valsalva, arrivando a conclusioni coerenti con le evidenze moderne. In seguito, avvalendosi di ulteriori studi, vengono analizzati alcuni fenomeni emodinamici: la formazione di vortici, la caduta di pressione, gli stress sviluppatisi sui lembi valvolari e la perfusione coronarica. Tali aspetti vengono osservati al variare di diversi parametri e in molti casi confrontando la radice dotata di seni di Valsalva con una radice priva di seni. Una piena comprensione della fluidodinamica dei seni di Valsalva è cruciale, poiché consente una corretta interpretazione delle alterazioni patologiche della radice aortica, e garantisce l’ottimizzazione delle strategie preventive e chirurgiche.
L'emodinamica dei seni di Valsalva
STAGNOLI, ALICE
2025/2026
Abstract
The sinuses of Valsalva are essential for the physiological function of the aortic valve and for preserving the aortic root. By generating vortical flow patterns, they facilitate the closure of the aortic valve and promote optimal coronary blood flow. After a brief description of the relevant anatomical region, the thesis presents the first studies on the subject conducted by the Bellhouse brothers. Before their work, only Leonardo da Vinci had recognized the importance of the sinuses of Valsalva, reaching conclusions that are consistent with current scientific evidence. Based on subsequent studies, several hemodynamic phenomena are then analyzed, including vortex formation, pressure drop, stresses acting on the valve leaflets, and coronary perfusion. These phenomena are examined under different conditions and, in many cases, by comparing an aortic root with the sinuses of Valsalva to one without them. A thorough understanding of the fluid dynamics of the sinuses of Valsalva is essential for the correct interpretation of pathological alterations of the aortic root and for the optimization of preventive and surgical strategies.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/115069