A novel approach for inferring phylogeny on a group of taxa. This is an alignment-free approach which considers the mutual occurrences of l-mers with at most k mismatches between a pair of DNA sequences in order to define a distance the species. This techinque, though quadratic in the average size of the sequences in time, leads to reliable phylogenetic trees. Tests have been performed on a mitochondrial DNA dataset and a retroid viruses dataset with optima results

Genome composition with mismatches and its application to phylogeny

Fracasso, Giulio
2014/2015

Abstract

A novel approach for inferring phylogeny on a group of taxa. This is an alignment-free approach which considers the mutual occurrences of l-mers with at most k mismatches between a pair of DNA sequences in order to define a distance the species. This techinque, though quadratic in the average size of the sequences in time, leads to reliable phylogenetic trees. Tests have been performed on a mitochondrial DNA dataset and a retroid viruses dataset with optima results
2014-04-15
l-mer, mismatches, phylogeny, tree, alignment-free
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12608/18277