Osteoarthritis is a complex disease referring to the degeneration of articular cartilage, which has poor intrinsic capacity of self-regeneration. In order to find a way to create a construct able to replace and regenerate this particular tissue, a functionalized biodegradable polymer via polymer brushes can represent a design for cartilage loss. The aim of this work is the study of the functionalization of a biodegradable polymer (PCL) surface with RGD peptide via PNIPAM brushes

Coupling of polymeric brushes functionalized with RGD peptide on PCL surfaces to increase cell adhesion

Dallan, Sara
2017/2018

Abstract

Osteoarthritis is a complex disease referring to the degeneration of articular cartilage, which has poor intrinsic capacity of self-regeneration. In order to find a way to create a construct able to replace and regenerate this particular tissue, a functionalized biodegradable polymer via polymer brushes can represent a design for cartilage loss. The aim of this work is the study of the functionalization of a biodegradable polymer (PCL) surface with RGD peptide via PNIPAM brushes
2017-12-11
functionalization, RGD peptide, polymeric brushes, PCL, tissue engineering, cartilage
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12608/24146