In recent years, substantial study has been conducted on the human gut microbiota, and our understanding of the resident species and their potential functional capacity is quickly expanding. The gut microbiota is a complex community of approximately 100 trillion microbial cells that regulate human physiology, metabolism, nutrition, and immune function. Disruption of the gut microbiota has been related to gastrointestinal diseases like inflammatory bowel disease and obesity, However in this study we concentrate on the importance of the relationship between Gut microbiota and the insurgence of liver diseases, We look at a number of recent research that have focused on improving our understanding of the complexity of intestinal communities, as well as their genetic and metabolic potential, and their effect on determining the pathogenesis on the gut- liver axis, We also discuss newly emerging genetic and other technologies for studying the gut microbiome, as well as the possibility of manipulating the gut microbiota as a therapeutic option for chronic liver diseases by fecal transplant.
In recent years, substantial study has been conducted on the human gut microbiota, and our understanding of the resident species and their potential functional capacity is quickly expanding. The gut microbiota is a complex community of approximately 100 trillion microbial cells that regulate human physiology, metabolism, nutrition, and immune function. Disruption of the gut microbiota has been related to gastrointestinal diseases like inflammatory bowel disease and obesity, However in this study we concentrate on the importance of the relationship between Gut microbiota and the insurgence of liver diseases, We look at a number of recent research that have focused on improving our understanding of the complexity of intestinal communities, as well as their genetic and metabolic potential, and their effect on determining the pathogenesis on the gut- liver axis, We also discuss newly emerging genetic and other technologies for studying the gut microbiome, as well as the possibility of manipulating the gut microbiota as a therapeutic option for chronic liver diseases by fecal transplant.
Gut-liver axis and liver diseases: the role of the gut microbiota and future implications
MATAR, IBRAHIM
2021/2022
Abstract
In recent years, substantial study has been conducted on the human gut microbiota, and our understanding of the resident species and their potential functional capacity is quickly expanding. The gut microbiota is a complex community of approximately 100 trillion microbial cells that regulate human physiology, metabolism, nutrition, and immune function. Disruption of the gut microbiota has been related to gastrointestinal diseases like inflammatory bowel disease and obesity, However in this study we concentrate on the importance of the relationship between Gut microbiota and the insurgence of liver diseases, We look at a number of recent research that have focused on improving our understanding of the complexity of intestinal communities, as well as their genetic and metabolic potential, and their effect on determining the pathogenesis on the gut- liver axis, We also discuss newly emerging genetic and other technologies for studying the gut microbiome, as well as the possibility of manipulating the gut microbiota as a therapeutic option for chronic liver diseases by fecal transplant.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/30702