In this thesis, different models which describe the cell growth in bacterial cells, are studied. In particular the effect of metabolic load is explored. Different growth rate functions are proposed and analyzed. Starting from the current literature, we first tested the already developed growth functions using mathematical simulations and highlighted the possible disagreements with the biological knowledge. The final goal is to identify a growth rate function that can be applied to models with different levels of complexity.
In this thesis, different models which describe the cell growth in bacterial cells, are studied. In particular the effect of metabolic load is explored. Different growth rate functions are proposed and analyzed. Starting from the current literature, we first tested the already developed growth functions using mathematical simulations and highlighted the possible disagreements with the biological knowledge. The final goal is to identify a growth rate function that can be applied to models with different levels of complexity.
Including Metabolic Load in Bacterial Growth Rate: a Systems Biology Approach
GAETAN, ELISA
2021/2022
Abstract
In this thesis, different models which describe the cell growth in bacterial cells, are studied. In particular the effect of metabolic load is explored. Different growth rate functions are proposed and analyzed. Starting from the current literature, we first tested the already developed growth functions using mathematical simulations and highlighted the possible disagreements with the biological knowledge. The final goal is to identify a growth rate function that can be applied to models with different levels of complexity.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/35245