The Dopaminergic Role in Healthy and Pathology

The correct functioning of human beings is affected, among other factors, by the activity neurotransmitters exhibit in the body. The present paper focuses on dopamine: a catecholamine neurotransmitter, acting through distinct pathways in the brain, and binding to different types of receptors. A summary of its main implicational functions, along with a brief historical perspective is presented. A further discussion about the most common disorders associated with dysregulation of this molecule is highlighted. The following will be considered: Substance-Related Disorders, Schizophrenia, Attention-Deficit Hyperactivity Disorder, and Parkinson’s Disease. Lastly, the focus will move to side effects related to medications involving this molecule.