This thesis explores the intricate intersection of sport nutrition, healthy aging, and optimal recovery strategies. The basic aim is to investigate the impact of targeted nutritional interventions on the physiological well-being, performance, and recovery of athletes engaged in a demanding activity. A significant component of the study involves the examination of specific supplementation strategies in basketball, focusing on the popular and emerging supplement Pyrroloquinoline Quinone. More specifically, this study explores the impact of PQQ supplementation on non-endurancetrained basketball players, investigating markers in blood, body composition, resting metabolism, and under exercise metabolism using a graded incremental test with the cycloergometer. The study is part of the PERA project. 20 subjects were randomized to consume 20 mg/day of PQQ or placebo (PLA). Both groups completed a six-week supplementation period. While the pre- and post-intervention assessments revealed limited statistical significance, the small sample size and inherent study limitations underscore the need for cautious interpretation of the results. Despite the inconclusive findings in conventional outcomes, the study emphasizes the potential effects of PQQ supplementation on the metabolomics data, also, it highlights the possibilities that each player’s individuality plays a key role on the response to the supplementation. The observed challenges and constraints suggest that further investigations with larger cohorts and a refined study design are essential to elucidate the potential benefits of PQQ supplementation.
Questa tesi esplora l’intricata intersezione tra nutrizione sportiva, invecchiamento sano e strategie di recupero ottimali. L’obiettivo fondamentale è studiare l’impatto di interventi nutrizionali mirati sul benessere fisiologico, sulle prestazioni e sul recupero degli atleti impegnati in un’attività sportiva. L’attenzione primaria dello studio prevede l’esame di strategie di integrazione nel basket. Entrando nello specifico, questo studio esplora l'impatto dell'integrazione di pirrolochinolina chinone (PQQ) su giocatori di basket, non tipicamente allenati alla resistenza, indagando i marcatori infiammatori legati all’attività sportiva nel sangue, la composizione corporea, il metabolismo a riposo e il metabolismo sotto sforzo utilizzando un test incrementale a step con il cicloergometro. Lo studio fa parte del progetto PERA. I dati si riferiscono a 20 soggetti, maschi e femmine, che sono stati divisi in modo randomico in due gruppi PQQ o placebo (PLA). Entrambi i gruppi hanno completato un periodo di integrazione di sei settimane, assumendo 20 mg/giorno di PQQ o di placebo (PLA). Sebbene le valutazioni pre e post intervento abbiano rivelato una significatività statistica limitata, la piccola dimensione del campione e i limiti intrinseci dello studio sottolineano la necessità di una cauta e ponderata interpretazione. Nonostante i risultati inconcludenti sui risultati convenzionali, lo studio sottolinea il potenziale significativo dell’effetto dell’integrazione sul metabolismo. Inoltre, si evidenzia la possibilità che l’individualità delle persone svolga un ruolo chiave nella risposta all’integrazione. Le sfide e i vincoli osservati suggeriscono che ulteriori indagini con coorti più ampie e un disegno di studio specificatamente più adeguato, siano essenziali per chiarire i potenziali benefici dell’integrazione di PQQ nei giocatori e nelle giocatrici di pallacanestro.
Effects of pqq supplementation in basketball players
ALFIER, AGNESE
2023/2024
Abstract
This thesis explores the intricate intersection of sport nutrition, healthy aging, and optimal recovery strategies. The basic aim is to investigate the impact of targeted nutritional interventions on the physiological well-being, performance, and recovery of athletes engaged in a demanding activity. A significant component of the study involves the examination of specific supplementation strategies in basketball, focusing on the popular and emerging supplement Pyrroloquinoline Quinone. More specifically, this study explores the impact of PQQ supplementation on non-endurancetrained basketball players, investigating markers in blood, body composition, resting metabolism, and under exercise metabolism using a graded incremental test with the cycloergometer. The study is part of the PERA project. 20 subjects were randomized to consume 20 mg/day of PQQ or placebo (PLA). Both groups completed a six-week supplementation period. While the pre- and post-intervention assessments revealed limited statistical significance, the small sample size and inherent study limitations underscore the need for cautious interpretation of the results. Despite the inconclusive findings in conventional outcomes, the study emphasizes the potential effects of PQQ supplementation on the metabolomics data, also, it highlights the possibilities that each player’s individuality plays a key role on the response to the supplementation. The observed challenges and constraints suggest that further investigations with larger cohorts and a refined study design are essential to elucidate the potential benefits of PQQ supplementation.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/61891