This thesis analyzes the Geometric Perfusion Deficit (GPD) as a new biomarker for retinal ischemia in diabetic retinopathy. It is identified using OCT angiography, a non-invasive method that allows for the investigation of retinal blood flow and, consequently, the identification of areas with reduced perfusion. The GPD is compared with other methods previously used to identify ischemic areas of the retina in this disease, and its limitations and future prospects are highlighted.
Questo elaborato di tesi analizza il Geometric Perfusion Deficit (GPD) come nuovo biomarker di ischemia retinica nella retinopatia diabetica. Viene individuato a partire dall'angiografia OCT che in modo non invasivo permette di indagare il flusso retinico e, di conseguenza, di evidenziare le zone di ridotta perfusione. Il GPD viene confrontato con le altre metodiche usate in precedenza per individuare le aree ischemiche della retina in questa patologia e vengono evidenziati i suoi limiti e le sue prospettive future.
Geometric Perfusion Deficit: un nuovo biomarker di ischemia retinica
CASTELLAN, ALICE
2024/2025
Abstract
This thesis analyzes the Geometric Perfusion Deficit (GPD) as a new biomarker for retinal ischemia in diabetic retinopathy. It is identified using OCT angiography, a non-invasive method that allows for the investigation of retinal blood flow and, consequently, the identification of areas with reduced perfusion. The GPD is compared with other methods previously used to identify ischemic areas of the retina in this disease, and its limitations and future prospects are highlighted.| File | Dimensione | Formato | |
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Castellan Alice Elaborato finale.pdf
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https://hdl.handle.net/20.500.12608/98029