The study described in this thesis, concerns an episode of mortality in meerkats with clinical signs attributable to the gastroenteric system. Animals came from a veterinary clinic specialized in new pets, where the deaths had occurred. The clinical presentation was suggestive of an infectious disease; with the principal suspect of carnivore protoparvovirus 1. The carcasses were submitted to necropsy, during which, for each individual, data like weight and sex have been collected, and samples from the organs of interest were collected, based on the diagnostic suspicion. Samples were subjected to nucleic acid extraction and molecular assays in search of carnivore protoparvovirus 1 (CPPV-1) and canine distemper virus (CDV) through real time PCR and real time RT-PCR. All samples tested negative for both pathogens. The results did not allow us to identify the etiology of the mortality in this group of meerkats, still ruling out the involvement of CPPV-1 and CDV. Further diagnostic tests will be necessary to identify causative pathogens and reconstruct the critical points in animal management that may have exposed them to infectious agents. This episode underlines the frailty of this species, whose captive breeding and the consequent exposure to common pathogens of dogs and cats, can constitute an important health risk that should be carefully contained through dedicated biosecurity measures.
Lo studio del caso descritto in questa tesi, riguarda un episodio di mortalità in suricati con sintomatologia a carico dell’apparato gastroenterico. Gli animali provenivano da una clinica veterinaria specializzata in nuovi animali da compagnia, dove erano avvenuti i decessi; la presentazione clinica era suggestiva di una patologia di origine infettiva, con sospetto principale di parvovirosi. Le carcasse sono state sottoposte a necroscopia, durante la quale, per ogni soggetto, sono stati raccolti dati come peso, sesso e tipologia di campioni di tessuti prelevati da organi di interesse, in base al sospetto diagnostico. I campioni sono stati sottoposti ad estrazione degli acidi nucleici e alla ricerca di carnivore protoparvovirus 1 (CPPV-1) e canine distemper virus (CDV) tramite real time PCR e real time RT-PCR. Tutti i campioni sono risultati negativi ad entrambi i test. Questi risultati non hanno permesso di individuare la causa della mortalità in questo gruppo di suricati, pur escludendo il coinvolgimento di CPPV-1 e CDV. Saranno necessari ulteriori test diagnostici per individuare gli agenti patogeni responsabili e ricostruire i punti critici nella gestione degli animali, che possono averli esposti ad agenti infettivi. Questo episodio sottolinea la delicatezza di questa specie, il cui allevamento come animale domestico e la conseguente esposizione a patogeni comuni nel cane e nel gatto, possono costituire un rischio sanitario importante da arginare con misure di biosicurezza dedicate.
Indagine diagnostica su casi di gastroenterite ad eziologia sconosciuta in suricati pet
DALAN, NICOLA
2025/2026
Abstract
The study described in this thesis, concerns an episode of mortality in meerkats with clinical signs attributable to the gastroenteric system. Animals came from a veterinary clinic specialized in new pets, where the deaths had occurred. The clinical presentation was suggestive of an infectious disease; with the principal suspect of carnivore protoparvovirus 1. The carcasses were submitted to necropsy, during which, for each individual, data like weight and sex have been collected, and samples from the organs of interest were collected, based on the diagnostic suspicion. Samples were subjected to nucleic acid extraction and molecular assays in search of carnivore protoparvovirus 1 (CPPV-1) and canine distemper virus (CDV) through real time PCR and real time RT-PCR. All samples tested negative for both pathogens. The results did not allow us to identify the etiology of the mortality in this group of meerkats, still ruling out the involvement of CPPV-1 and CDV. Further diagnostic tests will be necessary to identify causative pathogens and reconstruct the critical points in animal management that may have exposed them to infectious agents. This episode underlines the frailty of this species, whose captive breeding and the consequent exposure to common pathogens of dogs and cats, can constitute an important health risk that should be carefully contained through dedicated biosecurity measures.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/118656