Mathematical modelling of cancer: an ecological approach to the multiple myeloma bone disease

The insurgance of cancer disrupts the cellular environment, introducing many uncontrolled interactions within healthy tissues. It is possible, as we said, consider this process as an evolution of species where different types of cells are different species interacting with each other in an ecologic environment. Cancerous cells constitute an additional species, which entangles in the network and favors some species, damages others or does both at the same time. The coexistence of several cell types suggests that the dynamics may be driven by the mutualistic, exploitative, harmful or other type of ecological interactions. As a consequence, cancer modelling should be described in terms of evolutionary game theory.