This thesis investigates the neural underpinnings of emotion deficits in human morality and explores their relevance to acquired Antisocial Personality Disorder (ASPD). Beginning with an overview of moral emotions, the research employs functional magnetic resonance imaging (fMRI) studies to uncover the neural correlates of emotionally charged moral judgments. Findings indicate increased activation of vmPFC, OFC and STS, in response to morally unpleasant stimuli, supporting the involvement of distinct neural networks in emotionally charged moral judgment. Building on empirical studies and brain lesion research, the thesis integrates insights from studies that connect specific brain regions to moral judgment and emotional responses. Results point to a selective deficit in personal moral judgment in patients with vmPFC and OFC lesions, related to a failure in the synthesis of relevant emotional experiences with behavioral choices. Lastly, it focuses on acquired sociopathy, utilizing the cases of individuals with frontal lobe dysfunction, particularly in the orbitofrontal cortex (OFC) to unravel the neural intricacies of ASPD, highlighting distinct brain regions’ fundamental role in maintaining normal moral function and social behavior. In essence, this thesis provides a comprehensive exploration of the neural substrates governing emotion deficits in human morality, offering scientific insights into the intricate relationship between neural processes, emotions, human morality and acquired ASPD.
This thesis investigates the neural underpinnings of emotion deficits in human morality and explores their relevance to acquired Antisocial Personality Disorder (ASPD). Beginning with an overview of moral emotions, the research employs functional magnetic resonance imaging (fMRI) studies to uncover the neural correlates of emotionally charged moral judgments. Findings indicate increased activation of vmPFC, OFC and STS, in response to morally unpleasant stimuli, supporting the involvement of distinct neural networks in emotionally charged moral judgment. Building on empirical studies and brain lesion research, the thesis integrates insights from studies that connect specific brain regions to moral judgment and emotional responses. Results point to a selective deficit in personal moral judgment in patients with vmPFC and OFC lesions, related to a failure in the synthesis of relevant emotional experiences with behavioral choices. Lastly, it focuses on acquired sociopathy, utilizing the cases of individuals with frontal lobe dysfunction, particularly in the orbitofrontal cortex (OFC) to unravel the neural intricacies of ASPD, highlighting distinct brain regions’ fundamental role in maintaining normal moral function and social behavior. In essence, this thesis provides a comprehensive exploration of the neural substrates governing emotion deficits in human morality, offering scientific insights into the intricate relationship between neural processes, emotions, human morality and acquired ASPD.
The neural correlates of emotion deficits in human morality and ASPD
AMUNI, ROSE ASYA
2023/2024
Abstract
This thesis investigates the neural underpinnings of emotion deficits in human morality and explores their relevance to acquired Antisocial Personality Disorder (ASPD). Beginning with an overview of moral emotions, the research employs functional magnetic resonance imaging (fMRI) studies to uncover the neural correlates of emotionally charged moral judgments. Findings indicate increased activation of vmPFC, OFC and STS, in response to morally unpleasant stimuli, supporting the involvement of distinct neural networks in emotionally charged moral judgment. Building on empirical studies and brain lesion research, the thesis integrates insights from studies that connect specific brain regions to moral judgment and emotional responses. Results point to a selective deficit in personal moral judgment in patients with vmPFC and OFC lesions, related to a failure in the synthesis of relevant emotional experiences with behavioral choices. Lastly, it focuses on acquired sociopathy, utilizing the cases of individuals with frontal lobe dysfunction, particularly in the orbitofrontal cortex (OFC) to unravel the neural intricacies of ASPD, highlighting distinct brain regions’ fundamental role in maintaining normal moral function and social behavior. In essence, this thesis provides a comprehensive exploration of the neural substrates governing emotion deficits in human morality, offering scientific insights into the intricate relationship between neural processes, emotions, human morality and acquired ASPD.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/66094