Per- and polyfluoroalkyl substances (PFAS) are a class of persistent organic contaminants ubiquitous in the environment with a tendency to accumulate in water and soils. The consumption of vegetables contaminated by PFAS represents a path for the accumulation of these chemicals along the food chain, leading to risks associated with human and animal health. They can be assimilated by most plant species and are distributed based on affinity with the plant tissues, especially in vegetative tissues with high metabolic activity while less easily they accumulate in reserve tissues. Following the consumption of water and vegetables by animals, PFAS tend to bind serum proteins and increase in different tissues with varying degrees of specificity. Food products obtained from contaminated plants and animals can be a primary vehicle of exposure for consumers. In humans, PFAS can have serious consequences such as metabolic disorders, liver damage and cardiovascular disease. The control and mitigation of these substances are still in their infancy today.
Le sostanze per- e polifluoroalchiliche (PFAS) sono una classe di contaminanti organici persistenti ubiquitari nell'ambiente con tendenza ad accumularsi nelle acque e nei suoli. Il consumo di vegetali contaminati da PFAS rappresenta un percorso per l’accumulo di queste sostanze chimiche lungo la catena alimentare, portando a rischi associati alla salute umana e animale. I PFAS possono essere assimilati dalla maggior parte delle specie vegetali e si distribuiscono in base all’affinità con i tessuti della pianta, specie nei tessuti vegetativi ad elevata attività metabolica e con meno facilità nei tessuti di riserva. A seguito del consumo di acqua e vegetali da parte degli animali, manifestano la capacità di legarsi alle proteine del siero ed accumularsi in diversi tessuti con vari gradi di specificità e di concentrarsi progressivamente salendo nel livello trofico. I prodotti alimentari ottenuti da animali e vegetali contaminati possono essere un veicolo primario di esposizione per i consumatori. Nell’uomo i PFAS possono provocare gravi conseguenze come disordini metabolici, danni epatici e patologie cardiocircolatorie. Il controllo e la mitigazione di queste sostanze sono tutt’oggi ancora agli albori.
Le sostanze perfluoroalchiliche nella catena alimentare: dalla contaminazione dei suoli agli effetti sull'uomo
TRABUCCHI, ALESSANDRO
2021/2022
Abstract
Per- and polyfluoroalkyl substances (PFAS) are a class of persistent organic contaminants ubiquitous in the environment with a tendency to accumulate in water and soils. The consumption of vegetables contaminated by PFAS represents a path for the accumulation of these chemicals along the food chain, leading to risks associated with human and animal health. They can be assimilated by most plant species and are distributed based on affinity with the plant tissues, especially in vegetative tissues with high metabolic activity while less easily they accumulate in reserve tissues. Following the consumption of water and vegetables by animals, PFAS tend to bind serum proteins and increase in different tissues with varying degrees of specificity. Food products obtained from contaminated plants and animals can be a primary vehicle of exposure for consumers. In humans, PFAS can have serious consequences such as metabolic disorders, liver damage and cardiovascular disease. The control and mitigation of these substances are still in their infancy today.File | Dimensione | Formato | |
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Trabucchi_Alessandro - PFAS DEFINITIVA.pdf
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https://hdl.handle.net/20.500.12608/9866