This thesis explores the potential role of mindfulness-based practices as a protective factor against the development of post-traumatic stress disorder (PTSD) in adolescence, through a bibliographic review of the neuroscientific literature. The first chapter defines trauma and PTSD across its diagnostic categories, describing the neural correlates of the disorder, with particular focus on the specific effects of early trauma on the developing brain. The second chapter examines mindfulness programs (MBSR and MBCT) and the neuroplastic changes they induce, both in healthy adolescents and in adults diagnosed with PTSD, highlighting a significant overlap between brain areas damaged by trauma and those modified by contemplative practice. The third chapter develops an original preventive hypothesis, integrating the concepts of interoception, resilience, and autonomic nervous system regulation — drawing on Porges' Polyvagal Theory — with the concept of adolescent neuroplasticity. It is hypothesized that introducing mindfulness practices during adolescence, a period of peak brain plasticity, could preventively strengthen the neural circuits involved in emotional and stress regulation, thereby reducing vulnerability to PTSD following future traumatic exposures. The methodological limitations of the hypothesis and the possible practical implications for school-based and clinical interventions are also discussed.
Il presente lavoro si propone di esplorare il ruolo delle pratiche di mindfulness come potenziale fattore protettivo contro lo sviluppo del disturbo post-traumatico da stress (PTSD) in adolescenza, attraverso una revisione bibliografica della letteratura neuroscientifica. Il primo capitolo definisce il trauma e il PTSD nelle sue diverse categorie diagnostiche, descrivendo i correlati neurali del disturbo, con particolare attenzione agli effetti specifici del trauma precoce sul cervello in via di sviluppo. Il secondo capitolo esamina i programmi di mindfulness (MBSR e MBCT) e i cambiamenti neuroplastici che inducono, sia in adolescenti sani che in adulti con diagnosi di PTSD, evidenziando una notevole sovrapposizione tra le aree cerebrali danneggiate dal trauma e quelle modificate dalla pratica meditativa. Il terzo capitolo sviluppa un'ipotesi preventiva originale, integrando i concetti di interocezione, resilienza e regolazione del sistema nervoso autonomo — con riferimento alla teoria polivagale di Porges — con quello di neuroplasticità adolescenziale. Si ipotizza che introdurre pratiche di mindfulness durante l'adolescenza, fase di massima plasticità cerebrale, possa rafforzare preventivamente i circuiti neurali di regolazione emotiva e stress, riducendo la vulnerabilità allo sviluppo di PTSD in seguito a future esposizioni traumatiche. Vengono infine discussi i limiti metodologici dell'ipotesi e le possibili implicazioni pratiche per interventi scolastici e clinici.
Mindfulness e neuroplasticità adolescenziale: un'ipotesi preventiva contro lo sviluppo di PTSD
TIBERI, GIOIA NYCE
2025/2026
Abstract
This thesis explores the potential role of mindfulness-based practices as a protective factor against the development of post-traumatic stress disorder (PTSD) in adolescence, through a bibliographic review of the neuroscientific literature. The first chapter defines trauma and PTSD across its diagnostic categories, describing the neural correlates of the disorder, with particular focus on the specific effects of early trauma on the developing brain. The second chapter examines mindfulness programs (MBSR and MBCT) and the neuroplastic changes they induce, both in healthy adolescents and in adults diagnosed with PTSD, highlighting a significant overlap between brain areas damaged by trauma and those modified by contemplative practice. The third chapter develops an original preventive hypothesis, integrating the concepts of interoception, resilience, and autonomic nervous system regulation — drawing on Porges' Polyvagal Theory — with the concept of adolescent neuroplasticity. It is hypothesized that introducing mindfulness practices during adolescence, a period of peak brain plasticity, could preventively strengthen the neural circuits involved in emotional and stress regulation, thereby reducing vulnerability to PTSD following future traumatic exposures. The methodological limitations of the hypothesis and the possible practical implications for school-based and clinical interventions are also discussed.| File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12608/109798